'Builders' means Last Autumn-style Generator construction. (Unlike other 2 settings being simply difficulty options) Safety still applies, including poison gas, though no forced accidents and no Strike risk. (Just illness and probably accidents) Storms zero out progress on individual Generator part progress, but you have an option for rushing construction, which will result in flaws later. 50 days to get Generator online.
Generator Build Zone exists, is smaller, lets any building inside.
The Generator Optional Upgrade researches aren't in Endless. The Heat Zone 1 is eaten by the Generator build footprint, and so is useless if you built the Generator yourself!
Rifts map is nice. Too bad it's just the one map.
Settlements forces random events for some reason. You free-unlock the shipping building upon meeting a Settlement, then Administration upon building an outpost at a Settlement. Administration can be built anywhere (unlike On The Edge), but shipping has a map-specific designated build site using the Outpost icon. (Building it triggers the Outpost tutorial, actually) Rifts map inconveniently has it inside Generator Build Zone.
Settlements are the three from On The Edge, but they have less detailed dialogue. Have custom events like 'two settlements say a Steam Core is theirs: pick who to piss off/please, or take it for yourself to exhaust Favor, not affect Attitude, and instantly give you a free Steam Core'. Superstorms can disable a settlement for a few days, but you can ship emergency aid to instantly fix it. A loyal other settlement can fix it for you, too.
Max of 6 outgoing shipments in Endless for some reason.